It's far from my favorite passage of music from them, but I take that line to be Bono's near-death-inspired words of wisdom.. presumably speaking to his children, or to humanity as a whole.. a sort of "fuck the artifice/judgment/fear, and live as your whole self"
earlier he says "In your eyes alone I see the lights of home" before ending with "If only you could see yourself, If only you could see" which seems to lend itself to my half-baked interpretation
Deliberate callback to Iris