Maggie1 said:Never tried it, but I know it will make you very sick.
Never mix tranqulizers with alcohol. People have died from doing that.
Doozer61 said:Grapefruit juice is known to inhibit an enzyme system found in the small intestine that metabolizes some drugs prior to absorption into the bloodstream. This system is called CYP 3A4 and does play a role in the metabolism of certain drugs. Drugs that are affected by this interaction are metabolized less than usual when they are taken with GJ, allowing a higher amount to reach the bloodstream, and this will cause higher drug levels, sometimes with increases in clinical effects or side effects. GJ also affects a transporter called p-glycoprotein. The effects of this are less clearly defined, but p-glycoprotein is responsible for actively secreting some absorbed drugs back into the small bowel.
Got this info from the web.
Bonochick said:I've done it because my insomnia was so horrible that I was desperate for some good sleep. That was pretty stupid though, people shouldn't abuse meds like that.
JOFO said:
really?
how many glasses of wine and what dosage of xanax?
starsgoblue said:I'm curious as to why you're curious bout this JOFO.
I admit I've done it before and nothing bad happened, but apparently that is a huge exception to the norm....You aren't planning on experiementing are you? (puts on her mother hen hat)