There are loads, but at the moment three spring to mind.
In keeping with the Bond theme - Christopher Walken in View to a Kill, or Jack Nicholson in The Shining or Gary Oldman in anything he has played a villainous character in.
I love Super Mario World for SNES, and currently I'm obsessed with Baldur's Gate on PS2. On Gameboy Color (still haven't upgraded), I like the Pokemon series.