Sure.
I don't think any person (man or woman) is ever excused (justified) in cheating on their spouse. I do, however, acknowledge that people rarely cheat in a vacuum. At any given time, I'm working with several families going through these sort of crises. I've found that the cheater (again: both men and women) almost always has reasons that lead to their cheating. These reasons don't make their decision to break their vows ok. In the end, they alone are responsible for their decisions. But, more often than not, the act of cheating is the symptom of the problem and not the problem itself.
So I think it's important for both parties, the cheater and their spouse, to examine what they contributed to the breakdown of the marriage. I was working with a family recently whose oldest son had gone off the rails in the wake of his mother's infidelity and fallout from it. When I sat down with the parents, the father went to great lengths to explain why his wife was a whore. But as I started to get the whole picture I began to see a woman who loved her husband and her family, but after years of coming fourth in her husbands life (behind fishing, work and kids), she got involved emotionally with a guy from work that eventually led to a sexual encounter. Was she wrong? Absolutely. There's no way around that and it's up to her to earn back the trust of her family. But it's also pretty evident to see that the husband played a BIG role in his wife's affair. So, I challenged him to take a long hard look at what he contributed to the situation. The only way this marriage and family is going to be saved is if both husband and wife take a hard, honest look at what they're bringing to their marriage.
Hopefully I've done a better job explaining. If not I'll try later.