Compromised? Not really. Some might argue that any time you start over with an album simply because you don't have that "lead single," you're compromising your art. But as a commercial artist myself, I would say that you have to recognize your position in the business. What you create is entirely yours, but if it's intended to be consumed by the public, they'd better like it if you want to keep working.
I doubt Johnny Cash or Patsy Cline or Frank Sinatra or Elvis or the Beatles ever worried they were selling too many records. In the end, it's all about writing and performing good songs. All the rest is just silliness.