Interesting....without digging thru my archives that is the first I've personally heard Bono mention the gay aspect of the father/son thing. I understood it to be about a son who couldn't find acceptance from his father for any number of reasons, and that it was largely autobiographical due to the nature of the relationship he had with his own father. I can for some reason even remember someone from the band (pretty sure it was Bono) saying that it wasn't specifically written as a song for the gay community when people starting making the link between AIDs (due to the donation of proceeds) and the crossdressing video. Hmm.
Not that his new explanation bothers me in the slightest bit. I just recall an interview where he said something to the effect that One wouldn't be the first time the gay community had felt that a song had been written for them and went on to mention Twilight as another example.
At any rate, One is one of the top 10 songs of all time, and if that is what he now feels it means, that doesn't change my opinion one little bit.