It was very loud for both San Diego shows and yes think Bono could have had problems with that.
And yes think SD2 was a little louder than SD1. But it was pretty close.
Then ANA1 & ANA2 were louder than SD shows but I think part of that was the capacity is much greater between the venues (and think more state of the art acoustics at the Pond than SD Sports Arena)
But some still felt "lackluster" energy for the crowds to date... so dunno.