I watched the TED speech on the ONE site and not on You Tube. I usually don't read comments on any of Bono's appearances because I really don't care what some bored low lives full of jealousy and self-hatred are thinking about someone who actually gets up and does something.
Apart from that I think his speech was very good and fitting for TED. I've read a lot of comments on twitter from people who were there at the speech and from people involved in TED, but also from others who were very impressed. The important thing is to reach the right people. You Tube losers can think whatever they want.
Having Bono talking about statistics surely isn't the most interesting thing but it helps him to put forward his cases and be taken seriously by those who really matter. For TED, his speech was great, only a little fast because of the time limitations. I liked the graphics and I liked his speech. He's still the performer. I've seen better speeches by him but then again, the thing isn't a U2 show and not meant to make U2 fans happy, this stuff is about other issues, so I'm fine with it.
What I do notice, however, is that Bono and his work are mostly brought up in negative contexts here in the forum, it's mostly about other people hating on him or bashing him or posting stupid comments or about the media writing negative stuff and so on. There's a really strong tendency towards negativism which is a shame, because there's so much more to Bono and his work than that. For non-fans it must look like even U2 fans are only discussing the negative stuff on the forum which is sad.
I usually find his work and his speeches quite inspiring and I know a lot of people who do, too, but we're obviously not cynical enough to really take part in any "sophisticated" discussion about Bono or his political work.