Irishteen
Blue Crack Addict
U2 were the first band ever to play in the Point Depot - the Desire sequence in Rattle and Hum being the result. In case anyone dosen't know, that old warehouse was The Point - That was just before it was tidied up a bit to become a concert venue first time around in 1989.
Also Harry Crosbie, owner and developer of the venue is a great friend and supporter of the band. However he also has a commercial interest in maintaining the U2 "legend" around the point or the "O2" as it's now unfortunately known. Part of the wider development of the site is a planned U2 "Experience" - sort of a museum type attraction devoted to the band. I'd say U2 supporting Kings of Leon in order to be the first band to play the new venue is very very likely, not just for the kudos of being first, but also because Mr Crosbie has probably fronted up plenty of money as an incentive....
U2 recorded some of Rattle and Hum there but they were not the first band to play it
Huey Lewis and the News were the first
U2 recorded there before it was a venue, when it was basically just a warehouse
I'm sure some busker played there before them when it was a train station, so they would of beaten U2 too